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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '411e26059b108a9c5a244566658e7c01286b4d4c003e2c2fd67a61eef1a9c796' 
  AND token = 'RCtM7M4xYMWAOdLqWT0gjY8DeBj/aP82Z6zNmPE6Wdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}