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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d096ead19b2b5a9ddb085f0a9871f08d0de68d4d024c4a0cbaf3caebe3453cb' 
  AND token = 'PpBhCOhiLTFa/lE6DT6rFbmyx9TU1RrdrB5t/7gOxwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}