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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '151b5732e6138c09cfae7e9f246b0e0eb882207c38a09a917568be7cd07b0b7f' 
  AND token = 'WMCshxS2ngVrQWIwJGTSUrwS0m6gKylvlGw44F9gdSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}