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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8256283fdf442f5295f6c2a009bd995d8812d6f74c2406fc108de75631ef8b54' 
  AND token = 'qpEpw2iczEP17AsOr+IsvfbSlIEH6q8PgLoElEvP67Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}