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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '383c44a357746c8df3ba2fcd5f14eef4e00243659360f3adce4ec1b50b9d6180' 
  AND token = 'ljjGHPndEYBQH2FUo2x6EqY086AatPR+hEfRx46X8uU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}