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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abaf9895b28a99ef023a5e39c35cbea0cd4d275fcc39b5cb06536235b00c7f76' 
  AND token = 'vjyRZmOUFAoq44RY4QX+fkai0Qt3uzqBV0ELBY8PDUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}