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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b04d04c55a6b88a2e494d143c3f8d2fee172bdf5bad283c50e930d72fb3c531' 
  AND token = 'sXjz8SJfCj+EL+nkQmA9EThaKkpw1hVHNK8DcArib/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}