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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19d85d41fc529ce388ce1e7e2c6ef68a01ead401eca3a67054638688422e2eea' 
  AND token = '7GNdV+PXzusqu2wr3HwJuu6NWDAXwGi30aFYi1iQJcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}