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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d278b76ba387660497ae171469e01e81414373cbb55f70950283110b2a2a647' 
  AND token = 'nS3anE0UmB0wSBDk8t6GyUUHXSzGDtzTxH+YPymy+AA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}