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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '891b82d2a11c24643ff96a0f25992d5282178134ea7431016af8e689098570b5' 
  AND token = 'fz/uWUE/wcZWtoF9T3tJAqJEZM0NARWaKRmLmkb91LQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}