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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb1ad08ffd80fa936505816193a5aa1bd6373ec609d5c5b0cf00c9377d964655' 
  AND token = '2fA3+HKdRYbCEkAkfULmS3xUt6bbCSR1GJaqkxR5MUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}