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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed9157ebeeababe8ace9bb8a919f956d714682cdfe1d9e39bbce99f4099a7091' 
  AND token = 'DOVAn+lIusg+jc+QOV8LiBqzmkvlY0y/JG8RnkxlqbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}