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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d5036b86dd00f7d65e53b02e4f91dfb4eee051f33047f7b760767f41a082e77' 
  AND token = 'sCLSudlLVLObS/ac5NeNQQlWzwcK66z85zbAFOHyYAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}