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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64de43dd866539fb3d9bf27e5b6820a01eb1b2c76555dee970398ca1c56f2283' 
  AND token = 'W1Kp1tYV9jsQqsol+4CmFF80YLzKKsvabGzy9MLed6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}