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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6594294e0f354b1d1bac2e6dbbcd4ecf67db6c58eab00b60a2cfbae5fa548021' 
  AND token = '/KtniAuTeGB9rfTgjE2FiIvkZ4u4QSRbh1+2jZOkkbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}