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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16d5dec02b698922a9d6abe70ec5e877698536a9f45d9d361f66e61f0a769d2e' 
  AND token = 'MBlN2YnXhGXkRVY43nOMvd4mbyuYWqJhjFlAj4dxSrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}