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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6539b36507cd37a35f31301e84d24099aefadd0a45fee82169218ce72b4b1110' 
  AND token = 'ouNSOBBP4hU1RGdnWEbpSh76BqTkzjDHmj2N8/WbSgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}