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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e8917fd12897556205cbe060bff11518d2e89ecb221a16c37b59880d6d7ddd' 
  AND token = '5xlfu5k7n02M/Dp6DETuhlo8xQhj9Xz7VDNOYNo9lgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}