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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac7a429d16816234e1557499976a9d5c4b3169d8f54f6d5d69dc774eb8ff2d9c' 
  AND token = 'M0xyeo40QTmigYoPgvOr7wnSbwOyNFFU1qLoBlw6me4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}