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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7e525ae9d73781d23d3037eb73c25a48a29b082021d9bff86fa0af43bc442ad' 
  AND token = 'nvO8Zni2TTf7wxUfuAya0FyiDEFZPa2Z7NL4TDo/TqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}