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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd330bfa5868ca2fe125436d47f3aaaad8ec7a9222ee1c1cfb250e8b48c10a451' 
  AND token = '4Tuw0tizPRAXuSgjw8wg4yOtRpcjA/+9fTOiV6d7mzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}