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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10332dd88c6d32d7f894f366edd3fd095b77eacb57bf2202f593fea929e46f44' 
  AND token = 'ExDTc44LdSOlS/MxUopV4ssozuoWwUxsyVMCgMxYw3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}