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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd016a8a6e7f26179b3df643fbae2b53b30e456505c8fb2852671acf002d0d12e' 
  AND token = 'C4T9CN+np7ctuaVmkdKhF01uwav5b2dmc1kKlZCW0iY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}