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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a42a1ce7f9873a56f27e16d192e42e5e6b2b919a3618c1aac4a088c0cd321bf' 
  AND token = 'kfKsezOnxki3WnBS+GisLiDml4qhbu7AgtMdMrnupw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}