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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2925f842ebcc9f8a845bdd34c8b6d2659ef137551f4e465642ff040bf1df641' 
  AND token = 'Hxt3F5gC0KSeleGJlUjl0gV2Cofd+pUbUkHHEzPuqpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}