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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6978f2fc0e973accf0832f3a736b0aee748438779019995d3009b94e5f82e8c4' 
  AND token = '9VCe4M0TTlEEDQRio3S6Zbmy7gk7KAjyqqrszGHUgnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}