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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18b3983d8862ef3a741e2725879f8d378ce017386b53ecc10307afb252b4a6a9' 
  AND token = '2Cl1W82wVexfyWCAcqxErLhmNwu/QIKuxdcmfwm6f3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}