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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c65507f3cb1222c33e1b9597865de6f05b0390e0a1a7371e98a10985d8496260' 
  AND token = '5tiE4zUwMb8nkrbImbVNt3ehYpN4/6ppP1xhQHW5RqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}