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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dd942d31d4a9f7fd681528448b1a308c7af128b2c3825114bb27282e1949f90' 
  AND token = 'ozHeJuL0VHE+AM8evA4RrwT4k+2knCmhqfkj9oQ8UJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}