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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ae3c25d289ded267d0fa96e3c2724551aae332e9b26bc6ceb11d559bda8cfae' 
  AND token = 'UkULwOXryLgq8JQMloIDuYLhJycQZrVLuLJGEPMBxy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}