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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3dcb2429484580659a6626205a8aaaa2d70925c6c6ac26ee4f037b44c5c5b18' 
  AND token = 'o7UmU8zHMQOO6/ekuUZuqnZghm2lWU/S16NIBzsuKxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}