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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a09d9f4049614ce5a67a51a935d2656f7c6b288f2231d17ed25aa4482c3ebd2b' 
  AND token = 'oMOlvev3v8CzXtUv+B0kilzpxiy4LyKLYE0mYgoiRFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}