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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16066424cefd65bad1c6d4a5da5cb6659e5eccca3aa6dc7270c025fe42bf6189' 
  AND token = 'ID4i/6yxXabomA69b0Xq0QUlYh8LygF2mrU+ytIMRwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}