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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10a1ec1042e40e031859dca6f07de454e85e29d04cd98a369806f5ee6d8f0b31' 
  AND token = '2Rk4xHwFxy7ttuJbZ273XeVZ8X2wFNg9ogUogZhjLRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}