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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b0e721d2e689ea60fe1766157d48e910d18820eed9bd0125180c155ae5339a5' 
  AND token = 'njPnL1iT/bbrz5z1sNhcqBGX8CSkV0r1s+9GIcHYaxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}