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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59a927fd6ab129bf9101ef8e1d980a7826466b4710bd618b9d1cdcc1a4a702ff' 
  AND token = 'D7sQliwmpdhm6KAFsB4SRrMJ+jekobUInt+mnW8HyXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}