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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cef8e7a85b51d6c4ee8d8ad171d328eeb46ab2e5353f86038565d925dd7c2a3' 
  AND token = 'MBsfMKb62o+Tn1fC8nrW+5qHuE3j+mb/Nihxa+WkCqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}