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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b41d0304842ac24bf884c4309085bb81b602b7cd73c5e1db6e1ad268f28d5b3b' 
  AND token = 'Ec3AQFQBbNWYDUi7urfW5YF28V3f6/8ES/ta/Tc2+7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}