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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd279f12945387d9cd74ebcc38a557eb605f26f928ae0544f517277903a382bcd' 
  AND token = 'yxLArY+qh3QEHgAJ2+2lo2Bn1lk+OJ1q3oiI2UC5xDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}