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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '726d8252de4cbc8cb214d137f9eed437777ed8dfea1e8b08c9422064c66c6c18' 
  AND token = 'Vs7XiP9P+8gkzzAou8CFdMx6P+0l0jeluZc1TrbL+AA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}