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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5cdf6e909590b3a44d88390e4336834c36fb5cfac04d65fbc7145e16e5f00a1' 
  AND token = 'UWpgYPefuFpuigs6y/INXmXGKYbf7S5QuWfxjEhydEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}