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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d06538815dd69ef498208e2aa3bc36183c39b15661f64f6a67816b812a72942' 
  AND token = 'uSN8t5DPlPny2fw1So+lOOrimqb8wSUejx+So/S3pGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}