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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1865f152838f9188fcb9153c758e6ce8678d08c48698362235ae66848d0edadf' 
  AND token = 'IW9GlRojm9M7RxQvVu3G5TM6lN8rU2kSAFFV8WwQpE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}