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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd236b01cfa3f64593ad819e0d0a4369262532cb0c4fdb293fa9407493ea182e1' 
  AND token = '9I7aTEnMD9y9VfPFUcRr7Z1FbwuRBkvR24Vg2a8OmlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}