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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd85532a08c551c1e683df0e32c64c746b7695148e8f1f68f74612c187684e457' 
  AND token = 'EtDfEY1GPRhTg8i6qX+9msN+phWjo9cz9NX+049c0Pw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}