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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b5ecc9c29d320bd46f46b698c3617298f2d2f0414913937b030dd54ef79ce44' 
  AND token = '5tvCYbyM60mg5iLytjVKZeNsBbljH2rCfQb6dnVq8+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}