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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c7e733098739c6d250721be973462528c4235aa56dde768327cac1f802a2dc5' 
  AND token = '9qCsudq/OpXqHtijky6BjYdP8xCrph3QmuXbndKn+b4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}