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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65ee1596a8cbaa05dd98f972292fad2cf0d23a3d87c7a0e43e5de4d51d9f8aee' 
  AND token = 'pHT4aaLl1rA6xZle02AtGTxm8oh2q2RwhF59VyY6rOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}