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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '486dfd5d90657a2164e0ea7f0cdeb4e7db98bc5c8bd1c6f5534689b5311b7003' 
  AND token = 'SodAjA++6nfNB1npOL5eFUYh8bLm96ApgJ0hilUBFkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}