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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb70ccc74b73adc57bd2d2649c8e5518bfb37c278e973737a1446041040a1811' 
  AND token = 'XbD6+mcsnNMwov2tSu8/4OEutI1VKf+O7zkIiIe9V7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}